ST brings 32-bit-MCU possibilities to simple applications

first_img Continue Reading Previous Flex Power Modules adds active current sharing to DC-DC converterNext Murata’s ultra-small SAW devices address the needs of 5G STM32 microcontrollers from STMicroelectronics are now available in an 8-pin package, enabling simple embedded projects to leverage 32-bit performance and flexibility in a compact and cost-effective outline.The four new STM32G0 devices deliver a unique combination of 8-pin economy with a 64MHz Arm Cortex-M0+ CPU giving 59 DMIPS, up to 8Kbyte RAM and 32Kbyte Flash on-chip, and high-performing peripherals including a 2.5Msps ADC, high-resolution timer, and a high-speed SPI. With flexible mapping of I/O pins and internal MCU functions, designers can upgrade end-product functionality without trading board real-estate or bill-of-materials costs. The stability of the internal oscillator, which is accurate to ±1% over wide temperature and voltage ranges, also saves external clock components.Benefiting from the proven low-power design features of the STM32 MCU family, the 8-pin STM32G0 devices are ready to take over in energy-conscious applications governed by battery-capacity limits, eco-design legislation, or market expectations such as appliance energy ratings.The new MCUs also ease future scalability through the features available across the STM32G0 series, which offers up to 100 package pins, up to 512Kbytes Flash, additional high-performance analog peripherals, and cyber-protection features.The new 8-pin STM32G0 MCUs are available now in 6mm x 4.9mm SO8N, from $0.31 for 1000-piece orders of the STM32G030J6 Value Line MCU. The 8-pin Discovery kit STM32G0316-DISCO eases developers’ lives with quick and affordable evaluation. STM32G031J6, STM32G031J4, and STM32G041J6 Access Line MCUs are also available in SO8N, offering additional functionality including a hardware AES acceleration, Securable Memory Area enabling secure boot or firmware update, extra timers, and 96-bit unique device ID.Share this:TwitterFacebookLinkedInMoreRedditTumblrPinterestWhatsAppSkypePocketTelegram Tags: Chips & Components last_img read more

Mental Health Association of New York City Honors Patrick J Kennedy

first_imgOn Tuesday night the Mental Health Association of New York City (MHA-NYC) brought together over 300 supporters, guests and business leaders to call for greater awareness and support for the many faces of Mental Health.Mental Health Association Of NYC Gala Honors Patrick J. KennedyWABC Eyewitness News Anchor Bill Ritter hosted the emotional evening honoring Patrick J. Kennedy and focused on the personal stories of those challenged and the need for early detection and greater awareness.Every speaker on stage spoke about why they too were one of the many faces of mental health or a part of the vast support system connected in some way to the cause. Host Bill Ritter talked about the huge disparity between the numbers- one in four adults in this country has had a mental health challenge – and the resources devoted to mental wellness.Longtime MHA-NYC CEO and President Giselle Stolper highlighted the organization as a force for mental wellness as exemplified by such programs as the National Suicide Prevention Lifeline, Veterans Crisis Hotline, NFL Lifeline and 164 network crisis centers. “In 2015 alone,” she said “these programs provided life saving assistance to 1.5 million people people across the country. And locally, in partnership with New York City, we answered up to 12,000 calls a month from people in crisis.”Sarah Vander Schaaff, a writer and blogger, whose honesty and courage about her own obsessive compulsive disorder in the Washington Post received international acclaim, urged the audience to talk openly with their children and friends and embrace “the wisdom and help, medical and behavioral, that can lessen the pain and anxiety or depression and limit our mental well-being.”Antigone Davis, the head of Global Safety at Facebook, talked about their moving work with the National Suicide Prevention Lifeline to enable “compassionate connections on Facebook and our efforts to provide support for those dealing with depression and thoughts of self harm.” Working collaboratively with experts in the field, Facebook has developed enhanced tools and resources for when people encounter this kind of content. Davis added that this work was a labor of love for her, having lost someone she knew well to suicide while in college.It was 21-year-old D.J. Wilkerson, who brought the audience to its feet with his story of survival and ultimately triumph. Wilkerson, said he he had been called a “nothing” for much of his life. He began a self described “decline”, faced trouble with the law, dropped out of school and was hospitalized in a psychiatric ward of a hospital. He turned his life around, with the help of MHA-NYC’s Adolescent Skills Centers and beamed as he described his GED, two internships, successful job at GAMESTOP and educational and career dreams.The night came to a perfect close when Amy Kennedy, Education Director of the Kennedy Forum and wife of former Rhode Island representative Patrick J. Kennedy accepted the night’s award as a champion of mental health on her husband’s behalf. Kennedy said the lessons learned from Wilkerson’s story, and all those shared throughout the night, were a perfect example of the need for more education and early intervention to help all those struggling with mental health challenges.Event Chairs for the MHA-NYC 2016 Gala included: Jennifer Ashley, Ph. D., Global Director of Human Resources for CBRE, RIc Clark, Senior Managing Partner and Global Head of Real Estate at Brookfield, and CEO of Brookfield Property Partners, Charles P. Fitzgerald, founder and and Senior Managing Partner of of V3 Capital Management, L.P.Other notable guests included: Rebecca Jarvis, Chief National Correspondent ABC News, Tamsen Fadal, anchor at WPIX TV, former New York Rangers defensemen Tom Laidlaw, former New York Giants tight end Mark Bavaro and former New York Jets defensive back and broadcaster John Dockery.Sponsors for the MHA-NYC 2016 Gala included: Brookfield, CBRE Group, Inc., Cynthia Eckes, V3 Capital Management L.P., Cynthia Zirinsky, Jennifer Ashley, Ric Clark, Sheri & Kevin Danehy, Charles Fitzgerald, Diana Gaines, Alison Lewis & Newmark Grubb Knight, Frank, Alaina Melichar, Morgan Stanley, Alston & Bird, Balyasny Asset Management, EY, Facebook, Inc., Gracie Square Hospital, Bernie Groveman, Robert Gottesman, Haynes and Boone, LLP, Kelly Drye & Warren LLP, Meyer Mintz & Berdon LLP, Montefiore Medical Center, National Football league, Joseph F. Peyronnin, III and Susan Zirinsky, Ellen and Alan Rutsky, Anderson, McCoy & Orta, Beacon Health Solutions, Lawrence Calcano, Johnson &Johnson, Magellan Health, Paul Massey, Michael Nissan, Otsuka Pharmaceutical Development & Commercialization, Inc., Corbett Price, Lynn Sherman, S. Donald Sussman for Paloma Partners, Kenneth and Anna Zankel.last_img read more

No 16 Seeds Are Due

1991Arkansas2034Georgia St.144896.639.0 1997Kentucky2181Montana157897.727.9 1991UNLV2187Montana159298.443.1 1999Michigan St.2112Mount St. Mary’s142898.925.0 1985St. John’s1948Southern163687.783.7 1999Connecticut2140Texas San Antonio146898.625.3 2009North Carolina2103Radford152098.010.8 1986Kansas2059North Carolina A&T151797.179.6 2005Washington1964Montana150495.217.4 2013Kansas2024Western Kentucky149997.76.5 2012Syracuse2054UNC-Asheville161994.97.5 1992Duke2209Campbell134599.738.2 1990UNLV1989Ark.-Little Rock160794.048.0 2007Kansas2063Niagara161395.212.6 This data suggests that No. 16 seeds have in fact been pretty unlucky. On average, Elo would have given the No. 1 seed a 97.6 percent chance of winning each individual game; the range runs from 99.9 percent (Duke against Florida A&M in 1999) to 87.1 percent (Memphis against Oral Roberts in 2006). But given 124 chances to pull a rabbit out of their hats, No. 16 seeds “should” have come away with about three victories, according to Elo. Furthermore, the probability of them having gone winless is only about 5 percent. I wouldn’t call the No. 16s phenomenally unlucky — we’re talking about odds of about 20-to-1 against, not 20,000-to-1 against — but this confirms my intuition that they haven’t caught very many breaks.The good news for No. 16 seeds is that their situation has been improving very slightly. Since the tournament introduced its play-in game in 2001, the average No. 16 to play a No. 1 had an Elo rating of 1504; before that, their average rating was 1470. The play-in games are helpful to the cause of the No. 16 seeds in two ways. First, the truly execrable No. 16s, like Florida A&M in 1999 (which came into the tournament with a 12-18 record in the Mid-Eastern Athletic Conference), will be routed into the play-in game and will usually lose it instead of wasting one of the 16-seeds’ four opportunities. Second, the play-in winners will have a game of NCAA Tournament experience under their belts. That helps both in real life and for a team’s Elo rating, since Elo weights recent games (and especially recent tournament games) more heavily.So cheer up, Holy Cross, Hampton, Florida Gulf Coast University and Austin Peay State. Yes, you’re probably going to lose by 30 points. But sooner or later, one of you is going to make history.Check out FiveThirtyEight’s 2016 March Madness Predictions. 1988Purdue2015Fairleigh Dickinson150297.562.6 1988Oklahoma2043Chattanooga152995.759.9 Embed Code 1999Duke2295Florida A&M124899.925.3 YEARNO. 1 SEEDELONO. 16 SEEDELOTHIS GAMECUM. GAMES 1985Georgetown2135Lehigh125699.7%99.7% 1989Illinois2094McNeese St.150998.553.6 1994Arkansas2001North Carolina A&T136498.932.7 2011Duke2117Hampton147598.78.2 Every No. 1 vs. No. 16 men’s NCAA Tournament matchup, ever 2015Wisconsin2129Coastal Carolina148498.95.1 1990Michigan St.2052Murray St.160794.543.8 1987North Carolina2133Pennsylvania149298.869.3 2007Florida2046Jackson St.136598.712.4 2009Connecticut2024Chattanooga150397.411.1 1995Kentucky2115Mount St. Mary’s144399.031.4 By Nate Silver 2007Ohio St.2084Central Conn. St.155097.713.2 1992Kansas2106Howard141098.937.8 2003Arizona2069Vermont148198.520.3 It’s the sort of statistic that seems ripped from pages of the Washington Generals media guide. Since the men’s NCAA Tournament went to a 64-team format in 1985, No. 16 seeds are winless: an imperfect 0-124 record.No. 16 seeds can be pretty bad basketball teams, of course. Often, they’re teams from small conferences that won automatic bids by winning their conference tournament in a series of upsets after having barely cleared .500 during the regular season. (Small-conference teams that win both the regular season and their conference tournaments will usually wind up with No. 13, 14 or 15 seeds instead.) Furthermore, No. 16s have the misfortune of being matched up against No. 1 seeds, which are theoretically the four best teams in the country.But being bad is one thing; going 0 for 124 is another. My hunch is that No. 16 seeds have been unlucky not to have pulled off at least one upset.Consider that in the 1998 women’s NCAA Tournament, No. 16 seed Harvard (those plucky upstarts) beat No. 1 seed Stanford. And in the men’s tournament, several No. 16 seeds have come close to winning. Two of them, Princeton and East Tennessee State, lost by a single point in 1989 to Georgetown and Oklahoma, respectively. The next year, No. 16 seed Murray State took Michigan State to overtime before losing by four.Meanwhile, plenty of No. 15 seeds have won. Well, not plenty, but seven of them have upset No. 2 seeds. And No. 14 seeds have beaten No. 3 seeds 20 times. These results suggest that 16-versus-1 upsets ought to be possible, especially because there isn’t always a whole lot of daylight separating teams from one seed to the next. As its choices this year made clear, the selection committee is not infallible. Sometimes a team gets seeded as a 16 when it should probably have been a 14 or 15. Sometimes a No. 1 seed should have been a No. 2 seed. If a No. 15 seed can beat a No. 2 seed, then surely a 15-seed that’s mis-seeded as 16 can beat a 2-seed that’s mis-seeded as a No. 1.But we can be more precise about this. In building our NCAA Tournament forecasts this year, we developed an Elo ratings system for college basketball. Although our forecasts for this year blend Elo with several other computer ratings, we can run Elo-based projections for past tournament games going back as far as we like.Here, then, is how Elo would have forecast every past 1-versus-16 matchup on the day it was played. Once we figure out the No. 1 seed’s odds of winning each game, we can simply multiply the probabilities to figure out their cumulative odds of winning all 124. It’s a long table, so scroll down to the bottom for the punch line. 2014Wichita St.2041Cal Poly153997.45.9 1988Temple2058Lehigh152197.258.2 1993Michigan2095Coastal Carolina146398.534.6 1990Oklahoma2101Towson150498.651.1 2013Louisville2124North Carolina A&T145199.06.8 2001Stanford2113UNC-Greensboro145999.123.4 2006Villanova2035Monmouth150597.413.7 2013Gonzaga2032Southern143598.46.7 1992UCLA1959Robert Morris148597.036.6 2006Duke2084Southern143199.116.5 1995UCLA2059Florida Intl.131399.531.2 2009Louisville2059Morehead St.153497.010.1 1993Kentucky2066Rider142798.835.1 1995Wake Forest2077North Carolina A&T136199.131.7 1994Purdue2036Central Florida137399.034.2 2000Michigan St.2125Valparaiso147098.824.7 1991North Carolina2108Northeastern155797.241.9 1987Georgetown2015Bucknell148197.364.2 1994North Carolina2082Liberty145098.433.1 2011Kansas2117Boston U.157098.18.1 1996Kentucky2127San Jose St.157797.830.5 2007North Carolina2097Eastern Kentucky149498.413.5 2010Syracuse1986Vermont161992.68.8 1996Massachusetts2127Central Florida136599.629.4 1998Kansas2144Prairie View131799.626.4 1996Connecticut2134Colgate146698.829.1 2014Florida2086Albany155498.06.0 2010Duke2059Arkansas Pine Bluff142298.79.5 Our sports podcast Hot Takedown previews March Madness. 2008Memphis2023Texas Arlington144298.111.4 2000Duke2161Lamar137299.624.0 1997Minnesota2023Texas St.142398.327.4 1995Kansas2049Colgate147997.732.0 1987UNLV2064Idaho St.150697.367.4 2001Michigan St.2105Alabama St.145098.522.6 2010Kansas2161Lehigh151499.09.7 2002Kansas2066Holy Cross156197.321.9 2009Pittsburgh2021East Tennessee St.153696.210.4 2014Virginia2028Coastal Carolina145197.85.5 2006Connecticut2109Albany153197.916.2 2002Maryland2110Siena154298.321.5 1993North Carolina2147East Carolina148098.936.2 2012Kentucky2105Western Kentucky147698.57.9 2012Michigan St.2029Long Island U.157995.76.9 2003Oklahoma1975South Carolina St.147397.820.6 2004Stanford2041Texas San Antonio145098.418.5 2004Kentucky2085Florida A&M142199.018.3 1992Ohio St.2038Miss. Valley St.147598.138.3 2005Illinois2132Fairleigh Dickinson147599.017.2 1996Purdue2050Western Carolina153996.829.5 2002Cincinnati2055Boston U.149497.821.1 1993Indiana2130Wright St.155797.935.5 2004Saint Joseph’s1941Liberty144896.518.9 2015Duke2028Robert Morris155496.45.2 2005North Carolina2095Oakland151098.417.0 1998Duke2135Radford146298.826.5 2011Pittsburgh2008UNC-Asheville159494.58.3 CHANCE THAT NO. 1 SEED WINS … 2001Illinois2030Northwestern St.147598.023.0 2012North Carolina2059Vermont162996.07.2 1999Auburn1988Winthrop143897.425.7 2008North Carolina2141Mount St. Mary’s156398.311.6 1997Kansas2194Jackson St.145199.228.6 1991Ohio St.1997Towson153096.540.4 2006Memphis1931Oral Roberts162987.114.1 1986Kentucky2029Davidson152495.674.2 1989Oklahoma2028East Tennessee St.151796.254.4 2010Kentucky2029East Tennessee St.152696.59.8 2002Duke2193Winthrop141199.522.5 1989Georgetown2055Princeton153196.751.9 2013Indiana1986James Madison157494.56.2 1985Oklahoma1963North Carolina A&T154495.795.4 2004Duke2037Alabama St.133999.318.8 2011Ohio St.2115Texas San Antonio152398.78.0 1988Arizona2003Cornell149497.756.9 2003Texas1919UNC-Asheville127298.419.6 1986Duke2116Miss. Valley St.160797.577.7 1997North Carolina2099Fairfield143399.128.8 2005Duke2058Delaware St.146998.316.7 1994Missouri2003Navy141498.333.6 2015Villanova2086Lafayette149998.05.4 2001Duke2149Monmouth154498.623.7 2008UCLA2074Miss. Valley St.135099.512.3 1989Arizona2117Robert Morris136099.556.6 2003Kentucky2149IUPUI155998.119.9 2014Arizona2012Weber St.155795.75.6 1998North Carolina2155Navy146498.926.8 1986St. John’s2006Montana St.154094.470.1 2015Kentucky2158Hampton150399.05.4 2008Kansas2102Portland St.169895.511.8 1987Indiana2007Fairfield147398.066.0 More: Apple Podcasts | ESPN App | RSS | Embed 1990Connecticut2015Boston U.153396.446.3 1985Michigan2024Fairleigh Dickinson146198.082.0 2000Stanford2092South Carolina St.141798.424.1 2000Arizona1982Jackson St.139699.024.5 1998Arizona2159Nicholls St.152198.827.1 read more

Turks and Caicos AG Chambers defends Civil Servant in false news attack

first_imgFacebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, Turks and Caicos – July 17, 2017 – Fake or false news strikes again and this time it tried to take down the Registrar of Lands, Brandie Nova Anderson of Jamaica.  The Attorney General’s Chambers came to the defense of Ms Anderson and the Integrity Commissioned denounced that it is investigating the woman who has been Registrar of Lands since November 2014.No one knows who Joshua Pierre is, but that is the name put to a statement of a most damaging nature posted to social media about Anderson.It is said the statement was packed with lies and the AG has reported to the matter to the Police for investigation.  It was also explained in those Friday media releases that, “it is now very clear that some person or persons hiding behind the name “Joshua Pierre” made a malicious and damaging publication that has no basis in truth as it has been confirmed that no investigation into Ms. Anderson is being carried out by the Integrity Commission.”As for funds and how they are handled at the Lands department, there was this,   “The Government’s funds, including that, which have been appropriated to the Land Registry, are managed and paid through strict financial management and procurement procedures, and audited at the end of each Financial Year. There has been no finding to implicate Ms. Anderson of any wrongdoing since she commenced her service with TCIG.”The assault on the reputation of Anderson is called malicious.“All persons are reminded of the serious legal consequences of causing damage to the professional reputation of public officers who are merely seeking to carry out their functions in accordance with the high professional standards of the public service.”It was also explained that Ms. Anderson won the job of leading the Register of Lands through a fair and transparent process, a clean police record and she is also cited with having  “transformed the Lands Registry into an efficient operation in accordance with the requirements of the Registered Land Ordinance and has garnered the respect of her peers both within and outside of the public service.”#AGdefendscivilservant#IntegrityCommissiondeniesinvestigation#Andersonnotunderinvestigation#TCIGpublicservicestandard#FakenewsinTCI Related Items:#AGdefendscivilservant, #Andersonnotunderinvestigation, #FakenewsinTCI, #IntegrityCommissiondeniesinvestigation, #magneticmedianews, #TCIGpublicservicestandard Facebook Twitter Google+LinkedInPinterestWhatsApplast_img read more

San Diego City Council approves funding for homeless navigation center

first_img 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI) – The San Diego City Council yesterday approved funding for a navigation intake center for the homeless over the objections of four council members who said the center provides no shelter beds and guarantees no housing.The mayor agrees we need more housing but for now he’s focused on the short term needs of the homeless who are without shelter.In the meantime, the council has taken the lead on providing low cost housing by recently passed a resolution requesting each council district identify sites for 140 housing units that would get the city to 1260 units a number that would match the number of chronically homeless in the city.Additionally, the council hopes to expand the reach by including school districts land and property owned by the state. Steve Bosh, Posted: November 14, 2018 San Diego City Council approves funding for homeless navigation center November 14, 2018 Steve Bosh Categories: Local San Diego News FacebookTwitterlast_img read more

San Diego police make 62 DUI arrests during holiday period

first_img Posted: July 6, 2019 SAN DIEGO (KUSI) – The California Highway Patrol arrested 62 drivers for suspicion of drunk driving in San Diego County over the holiday period, officials said today.While there were no fatalities on county freeways this year, the CHP said 17 people were killed in California during the July Fourth holiday period. The CHP holiday reporting period was from 6 p.m. Wednesday to 6 a.m. Saturday.The arrests for suspicion of DUI in the county increased over last year’s holiday period by 28. The CHP only tracks DUI arrests made by CHP officers.Statewide, three pedestrians were killed during the holiday period in the CHP’s jurisdiction. There were two motorcycle deaths reported statewide.This year there were 17 driving fatalities in California, as reported by all law enforcement agencies. Last year there were also 17. This year there were 839 arrests by CHP officers for suspicion of DUI throughout California. There were 389 last year. San Diego police make 62 DUI arrests during holiday period July 6, 2019 Categories: Local San Diego News FacebookTwitter KUSI Newsroom KUSI Newsroom, last_img read more

GameStop To Hold Fundraising Campaign For Autism Speaks This May Increase Employment

first_img(NOTE: GameStop is located at 246 Main Street in Wilmington.)GRAPEVINE, TX — GameStop is once again partnering with Autism Speaks to help increase awareness, understanding and acceptance of people with autism spectrum disorder. Throughout May, the video game retailer is focusing its annual in-store autism awareness campaign on raising funds for the newly launched NXT Gen Coders Program powered by GameStop and administered by Autism Speaks, aimed at increasing coding and programming skills for people with autism.From May 1 through May 31, GameStop will host its third annual in-store autism awareness campaign with 100 percent of donations going to Autism Speaks and helping fund the NXT Gen Coders Program. This program, powered by GameStop and administered by Autism Speaks, will focus on opportunities for coding and programing skill development for people with autism, so that they may be better equipped to take advantage of the one million jobs that the U.S. Bureau of Labor Statistics estimates will be open in the coding industry by 2020.With the vast majority of adults with autism unemployed or underemployed, GameStop and Autism Speaks are collaborating on the NXT Gen Coders Program to give talented young men and women a path to careers that match their training, abilities and interests.“We are proud to continue our commitment to raising awareness and providing support to the individuals and families impacted by autism,” says Jason Cochran, senior vice president of Store Operations for GameStop. “Through our ongoing partnership with Autism Speaks and the newly launched NXT Gen Coders Program, we are taking extra steps to provide individuals with autism the job and life skills they need to help them enjoy a more fulfilling life.”During this year’s campaign, GameStop is offering three ways guests can contribute to support people with autism:For the first-time, guests will have the option to donate up to 100 percent of their trade-in value to charity when they bring to GameStop their unused video game hardware, software, accessories, or consumer electronics.Donate $1 or more in-store or on GameStop.com and GameStop will provide triple PowerUp Rewards points on the donation amount.Donate PowerUp Rewards points to Autism Speaks in the PowerUp Rewards Center.GameStop’s continued support of Autism Speaks follows several successful campaigns since the partnership began in 2016, with more than $2.4 million in donations raised to enhance the quality of life for children, adults and families impacted by autism.“We appreciate GameStop’s generosity and commitment to the autism community,” said Autism Speaks President and CEO Angela Geiger. “Each year, 50,000 young people with autism enter adulthood, expanding a talent pool that is largely untapped. Creating employment opportunities requires innovative solutions, which is why we’re excited about the NXT Gen Coders Program.”(NOTE: The above press release is from GameStop.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedBUSINESS BRIEF: GameStop Awards $250,000 In Grants To Increase Employment Readiness For People With AutismIn “Business”GameStop Partners With Autism Speaks for Autism Awareness MonthIn “Business”GameStop Collects $1.2 Million in Donations During Autism Awareness MonthIn “Business”,Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.last_img read more

What AncestryDNA taught me about DNA privacy and the complex world of

first_img Share your voice Tags The hardest thing about having your DNA sequenced is generating a teaspoon’s worth of spit.They don’t tell you this in the marketing materials for your typical at-home DNA test kit, but producing enough saliva to fill a pen-sized tube up to its high spit mark is hard work — and strangely nerve-wracking, too.I sneak into an unused meeting room, chewing on air to generate slobber. The kit has two tubes. One, now full of my spit, and a second smaller tube with a chemical mix that stabilizes DNA. After uniting the two tubes, I stick the pale blue spit-mix into a box and mail it off to AncestryDNA, the genetics arm of the world’s largest genealogy company, Ancestry.In 2012 Ancestry launched the AncestryDNA service, which provides paying users the ability to build a timeline of their genes, search for relatives and understand what geographic regions their DNA originates from. Ancestry has sold 14 million kits since launch, and the number continues to grow as curious consumers turn to DNA to unravel their histories. The AncestryDNA kit Chris Linton So it’s not just me caught up in this craze — search for “Ancestry DNA results” on YouTube and you’ll find an entire subculture propped up by enthusiastic explorers probing their genetic histories. There’s a whole genre of evening TV dedicated to analyzing the family histories of the rich and famous. Over the last two years many DNA kit manufacturers have begun marketing their products as “perfect gifts.” In the 2018 Thanksgiving period, AncestryDNA broke its November sales record. Your DNA story has become this year’s hottest Christmas gift! Consumer genealogy tests have become big business practically overnight. Why are we so interested in finding out the secrets of our DNA?”I think the major appeal of DNA testing is to find out something new about us,” says Caitlin Curtis, a population geneticist at the University of Queensland. That’s certainly true for me, at least. My first thought is what revelations my spit might teach me about myself. But in the quest for answers, do we truly understand what kind of information we’re giving up?Related: The best DNA testing kits for 2019 Digging into your DNAThe almost unfathomable complexity of all life on Earth, from bacteria to humans, relies on DNA, but the DNA code itself is made up of just four letters: A, T, C and G.These letters, known as bases, always pair together the same way — A with T, C with G. The order in which these letters are arranged is what makes us different and gives us our unique traits. And because we hand parts of our DNA from parent to offspring, it also links us to the past. We just need to be able to “read” it and put all those bases in order. This is known as DNA sequencing. In the future, not even your DNA will be sacred Genealogy site credited with helping ID Golden State Killer suspect Best DNA Ancestry Testing Kits Now playing: Watch this: The genealogy craze 8 7:06 DNA data storage could solve a big problem Comments Who does that data belong to? It can be confusing, especially when these companies make deals with huge corporations to share their data.”I believe that there is an ethical obligation for these companies to be very upfront, honest and explain in simple terms to people what might happen to their data after they take a test, but that is not always the case,” says Curtis.AncestryDNA’s terms and conditions state that it “does not claim any ownership rights in the DNA submitted for testing” but by submitting a sample you effectively “grant AncestryDNA … a royalty-free, worldwide, sublicensable, transferable license to host, transfer, process, analyze, distribute, and communicate your Genetic Information for the purposes of providing you products and services.”It may be my DNA, but how it’s used in the future is something that AncestryDNA decides. However, there is a failsafe. The nuke-it-all option.”It’s your data, you should be able to do with it what you want,” Starr says. “If you decide at some point that you don’t want us to have it anymore, you can tell us to delete it and you can even tell us to destroy the DNA sample.”DNA as data”The biggest danger with handing control of your DNA data is the potential for discrimination based on that information,” says Curtis.Now that even our DNA is being digitized and stored in the infinite online filing cabinet of the World Wide Web, we must confront a reality in which our own genetic makeup can be hacked, stolen or used against us.”There are some parallels to broader conversations around how to govern our personal digital data online – and the possibility for it to be used in unanticipated ways in the future,” she continues.When we began signing up, en masse, for social media services such as Facebook and Twitter over a decade ago, we blindly shared our best baby photos and snarkiest thoughts with reckless abandon. Little did we know our personal data was being siphoned off insidiously and then used to target us in ad campaigns. And that data is still being generated and used today — Facebook gets to know exactly who we are in a matter of months. A cautionary tale, it would seem, considering genealogy testing has undergone rapid growth in the last two years. And though the science is getting better, the regulations and potential pitfalls are becoming harder to nail down.”It’s a complicated issue because in some countries there is protection against discrimination, and in some countries there are very few laws about what you can do with genetic data,” explains Curtis. In the US, the Genetic Information Nondiscrimination Act of 2008 prevents health insurers and employers from discriminating against you based on your genetic profile. However, in Australia, insurance companies can discriminate based on the results of a DNA test, increasing premiums or completely excluding coverage for certain diseases.Cool. Cool cool cool. Almost none of this research was done before I spat into a tube six or seven weeks ago, and now I realize my nerves weren’t about how much spittle I could produce. I jangled because I was diving headfirst into a world I thought I understood, but actually knew hardly anything about. There were voices gnawing at my subconscious. A devil on one shoulder, an angel on the other. One quietly trying to tell me that it’s kind of weird to give a private, multinational company access to the immutable information that can be used to identify me — and only me. The other saying “what can you lose?”You already know which one I listened to. I click through ready to solve this admittedly feeble personal mystery. But there are no shocking revelations. I end up with an ethnicity estimate that puts my DNA origins at 55 percent England, Wales and Northwestern Europe and 44 percent Ireland and Scotland.However, there’s also a zero to 1 percent chance my DNA comes from a region in West Africa that AncestryDNA pegs as relating to “Benin/Togo.” Surprising to me, but not unusual, according to Starr.”A 0-1 percent would say there might be something interesting here, but there might not,” he says. A result such as this might “fall out” in the future, as AncestryDNA’s databases continue to be refined by additional samples and research programs. My ethnicity estimate is only one half of the picture, however, because I can also look at my DNA matches, which directly correlates my DNA with that of other users in Ancestry’s database. In my case, it throws up two matches that AncestryDNA classes as “second cousins” — pretty close relatives of mine, according to my genes.I’ve never seen these people.And this is a caveat for the AncestryDNA kit. Your DNA might kick up matches with people you’ve never seen before, but if you want to fit them into your family tree, you need to subscribe to the other side of the Ancestry business to pore over how you might, potentially, be related to one another.  dnastoryMy ethnicity estimate had me at a 0 to 1 percent chance of having genetic heritage in Benin/Togo Jackson Ryan Digital DNA trailIn January, Buzzfeed News reported that FamilyTreeDNA, another huge provider of at-home DNA kits, had given the FBI access to its database of over a million profiles. The company provides the FBI with the ability to upload genetic profiles from crime scenes to FamilyTree’s database, which may aid them in genetically hunting down criminals. However, FamilyTree didn’t notify users that their genetic information might be used this way before giving the FBI access. And while there have been high-profile, beneficial uses for law enforcement — the apprehension in 2018 of a suspect in the Golden State Killer case, for example — it does raise issues about how this highly personal information may be shared in the future. Particularly concerning is the idea that you don’t even have to share your own DNA data for it to become searchable because your third cousin has already uploaded their own profile. It’s your data, you should be able to do with it what you want. Barry Starr The technology to perform this task has improved dramatically over the last two decades, driving the costs of DNA sequencing down from $10,000 in 2011 to $1,000 in 2017, according to the US National Human Genome Research Institute. Those advances have trickled through to the commercial sector, allowing a myriad of companies, from startups to huge public organizations, to develop their own at-home DNA testing kits.Kits provide customers with an estimation of their genetic histories, ancestries and even potential health issues they might run into. But going from a saliva sample to a genetic history solution is a complex process involving overwhelming amounts of data and statistical analyses that often confound more than they clarify. “There is a general lack of knowledge about how the whole process of ancestry testing works,” Curtis says. “People’s perceptions of the results might be different from the way a genetic scientist might interpret the results.”I’m pretty well versed in the complexities of molecular biology, but after sending my spittle away I become acutely aware that I have no idea how AncestryDNA’s test works. I know it’ll give me an “ethnicity estimate” and tell me my “DNA story,” but beyond the marketing buzzwords I’m in the dark.Science, math and dataAncestryDNA uses a database that contains more than 16,000 reference DNA samples from 43 regions around the world. About 12,000 of these samples come from Ancestry users who opt in and allow the company to use their DNA for research purposes, while the remaining reference samples come from public databases such as the 1000 Genomes Project.”We find people with long family histories from a certain part of the world and we analyze their DNA, and their DNA becomes, by definition, 100 percent from the region” says Barry Starr, director of scientific communications at AncestryDNA. The science of it is complex: The procedure splits up a DNA sample into 1,001 different “windows,” as Starr calls them. All up, those 1,001 windows look at approximately 700,000 spots in the DNA code. When you take the test, every window is compared to the 1,001 windows in a reference sample, and that occurs for each of AncestryDNA’s 43 regions.If 500 of those windows match, say, a Canadian region, then by AncestryDNA’s definition, I am 50 percent Canadian. Sci-Tech “It really is cutting-edge science, and as the field advances we advance with it and so provide updates to consumers when we have made changes based on the progression of the science,” says Starr.CNET rates AncestryDNA as having one of the best kits available, in large part thanks to its huge database. But testing doesn’t just rely on database size — where the data comes from is also important. Almost 75 percent of AncestryDNA’s ethnic regions skew toward European descent, so detailed estimates of ethnicity from other regions is difficult to obtain at present. A study, published in Nature in 2016, suggested that the scientific inquiry into genomes was also suffering from bias.With fewer reference samples from both consumers and scientific research available in regions of Africa and Asia, accurate estimates for genetic heritage in those locations are more prone to error. “Everyone started out in Africa, and a small set of them moved out of Africa and colonized the world,” explains Starr. “The genetic diversity within Africa is huge compared to the rest of the world, which means you need larger reference panels.”And the results of different genealogy tests may show marked differences. For instance, 23AndMe, a rival genealogy company based in California, has a more extensive catalogue of East Asian regions than AncestryDNA. Providing DNA samples to both companies could lead to completely different ethnicity estimates. It’s not that your DNA has changed — but the different databases and algorithms used to calculate it have. ancestrydnakit-3crop Ian Knighton/CNET My DNA storyI’m not exactly sure where I come from.An educated guess would say this impressively pale skin hails from a region localized entirely within Britain. There could be some Scottish in there. Maybe a hint of Irish, too. I don’t think there’s lots of room for suspense or intrigue here.Four weeks after I spat in a tube, my email chimes. Your AncestryDNA results are in!last_img read more

Tata Motors subsidiary Jaguar Land Rover to hire 5000 staff in Britain

first_imgPhoto taken on July 6, 2016 shows the displayed Jaguar XE car at the 7th International Auto Exhibition 2016 in Xi’an, capital of northwest China’s Shaanxi Province.IANSBritain’s biggest carmaker Jaguar Land Rover (JLR) will hire 5,000 staff as it boosts its skills in autonomous and electric technology, a welcome business endorsement as Prime Minister Theresa May starts Brexit talks after a botched election.JLR, which employs more than 40,000 people globally, said it would hire 1,000 electronic and software engineers as well as 4,000 additional personnel including in manufacturing, most of whom will be based in Britain.The recruitment process will take place over the next 12 months, during Britain’s talks to leave the European Union, which carmakers have warned must result in a deal which retains free and unfettered trade to protect jobs.May lost her parliamentary majority in the June 8 general election that her Conservatives fought on the promise of a clean break with the EU single market and customs union.The renewed political uncertainty has seen business confidence tumble in recent days, according to surveys and business groups.Hours before the talks were due to begin in Brussels, the heads of the UK’s biggest business lobbies called on the government to engage “continuously” with UK business interests and strike a deal that preserves the benefits of EU membership including tariff-free trade, guarantees for EU citizens living in the UK and minimal customs formalities.Finance minister Philip Hammond said leaving the EU without an agreement would be a “very, very bad outcome for Britain” and he wanted an exit that would support employment and investment.”When I talk about a Brexit that supports British jobs, British investment and British business I mean a Brexit that avoids those cliff edges,” Hammond said in an interview with BBC television on Sunday.JLR, which is owned by India’s Tata Motors, will build its first electric vehicle, the I-PACE, in Austria but has said it wants to build such models in Britain if conditions such as support from government and academia are met.Automakers are racing to produce greener cars and improve charge times in a bid to meet rising customer demand and fulfil air quality targets but Britain lacks sufficient manufacturing capacity, an area ministers have said they want to build up.JLR, which builds just under a third of Britain’s 1.7 million cars, has said half of all its new models will be available in an electric version by the end of the decade, requiring new skills among its staff.last_img read more