About the authorFreddie TaylorShare the loveHave your say Dele Alli insists Spurs players behind Pochettinoby Freddie Taylora day agoSend to a friendShare the loveTottenham star Dele Alli believes that everyone at the club is firmly behind their manager Mauricio Pochettino.Spurs are struggling for confidence and form, especially in the Premier League.It has seen them slip in the top four race and prompted talks about Pochettino’s future at the club. But Alli insists every one of Spurs’ players is behind the Argentine coach.He told reporters: “Yeah, 1,000 per cent [players are behind Pochettino].”A lot of us would not be where we are now if it was not for him. All we can do is thank him.”We have always trusted him 100 per cent and we are going to keep doing that. We are a team.”When things are not going our way, it is easy for people to try and get at the manager but we need to look at ourselves as players.”We’re doing that and we are going to keep working hard.”
Georgia State, the No. 14 seed in the West Region, just ended the game on a 13-0 run to shock No. 3 seed Baylor, 57-56. Georgia State guard R.J. Hunter, the son of GSU head coach Ron Hunter, hit the game-winning three-pointer from way downtown with 2.8 seconds remaining.Hunter struggled much of the day, scoring just two points in the first half. His dad coached the whole game in a rolling stool after tearing his left achilles tendon celebrating the team’s Sun Belt Conference championship last week.This is what happened to Ron Hunter when R.J. made his game-winner. March Madness is amazing.
Related:World’s 1st LNG-Powered Aframax Completes Maiden VoyageShell’s Cardissa Carries Out Its 1st LNG Ship-to-Ship BunkeringSovcomflot Reports Significant CO2 Cuts from New LNG-Powered Tankers,Related:World’s 1st LNG-Powered Aframax Completes Maiden VoyageShell’s Cardissa Carries Out Its 1st LNG Ship-to-Ship BunkeringSovcomflot Reports Significant CO2 Cuts from New LNG-Powered Tankers zoomIllustration. Image Courtesy: Sovcomflot/Navigate PR Korolev Prospect, Sovcomflot’s LNG-fueled Aframax crude oil tanker, began a transit of the Northern Sea Route (NSR) on August 26, 2019.The 123,492 cbm vessel will become the first such large-capacity crude oil tanker to travel the entire length of the NSR using only clean-burning LNG fuel, Sovcomflot said.The 113,200 dwt tanker is carrying a cargo of crude oil from the Russian port of Murmansk to China.The journey along the NSR, from Cape Zhelaniya to Cape Dezhnev, will take about eight days, with vessel moving at the expected average speed of 12 knots, according to the Russian shipping company.While transiting from the Laptev Sea to the East Siberian Sea, the vessel will follow the ‘Tikhonov’ deep-water route that lies north of the New Siberian Islands, which was first opened for commercial shipping in 2011 by SCF’s tanker Vladimir Tikhonov.Compared with standard marine fuels, vessels using LNG fuel achieve a significant reduction in vessel emissions whilst also improving the ship’s energy efficiency.Today, Sovcomflot has six LNG-fueled crude oil tankers in operation, including Korolev Prospect, and five more under construction.Delivered by Korean shipbuilder Hyundai Samho Heavy Industries in February 2019, Korolev Prospect features a length of 250 meters, a breadth of 44 meters, and an ice class of 1A hull.Sovcomflot’s fleet currently includes 146 vessels with a total deadweight of over 12.8 million tons. More than 80 vessels have an ice class.
Reviewed by Kate Anderton, B.Sc. (Editor)Apr 16 2019Cancer cells are characterized by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells. Many studies devoted to new chemotherapy treatments aim to induce apoptosis and thus remove cancer cells or reduce the size of the tumor. Scientists at the Institute for Research in Biomedicine (IRB Barcelona) have demonstrated that the protein TP53INP2 plays an important role in the induction of cell death. This finding could be relevant in the treatment of certain types of cancer.”We observed that when cells have high levels of TP53INP2, apoptosis is accelerated when specific receptors on the cell membrane are activated. In contrast, the cells that did not express this protein were more resistant to apoptosis,” comments Antonio Zorzano, head of the Complex Metabolic Disease and Mitochondria Lab at IRB Barcelona.Related StoriesBacteria in the birth canal linked to lower risk of ovarian cancerSugary drinks linked to cancer finds studyStudy reveals link between inflammatory diet and colorectal cancer riskPublished in EMBO Journal, this study describes how this protein increases the efficacy of certain chemotherapy treatments, such as TRAIL. “We demonstrate that TP53INP2 makes cancer cells more sensitive to death signals, including TRAIL,” explains Saška Ivanova, postdoctoral fellow at IRB Barcelona and first author of the study.TRAIL holds great promise for the treatment of cancer because it can selectively induce the death of cancer cells. Since its discovery in 1995, many clinical assays have been devoted to this drug. However, not all patients with cancer respond to this treatment. Researchers at IRB Barcelona have confirmed the relation between high levels of TP53INP2 and an enhanced response of liver and breast cancer cells to TRAIL.One of the issues regarding TRAIL is the need to identify patients likely to respond to this treatment, as TRAIL can enhance tumor progression in some types of cancer. “We propose the protein TP53INP2 as a potential marker to identify patients that could benefit from treatment with TRAIL,” explains Zorzano, full professor at the University of Barcelona and CIBERDEM researcher.Personalized medicine, an approach that allows treatment to be adapted to the characteristics of each patient, emerges as one of the health care strategies with most potential. Knowledge of the type of cancer and selection of the most efficient treatment in each case will increase patient survival. However, biomarkers are needed. In this regard, this study offers a new approach to support physicians in the selection of personalized treatments.”We are now extending the study to other types of cancer, such as lung cancer, to confirm whether TP53INP2 also improves the response to treatment with TRAIL,” adds Ivanova. Source:https://www.irbbarcelona.org/en/news/researchers-identify-a-new-biomarker-for-personalised-treatments-against-cancer
Why driverless vehicles should not be given unchecked access to our cities Provided by University of Surrey More information: Autonomous vehicles and the future of urban tourism. www.academia.edu/37663136/Auto … ure_of_urban_tourism Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Credit: CC0 Public Domain In the first study of its kind, published in the Annals of Tourism Research, academics from the University of Surrey and the University of Oxford have examined how Autonomous Vehicles (AVs) may have a substantial impact on the future of urban tourism. When we think of automated vehicles it seems to be a topic that sits firmly in science fiction, from cars with character in The Love Bug (1969) and Knight Rider (1982) to more recent practical representations in Minority Report (2002). However, according to the new research by Professor Scott Cohen (University of Surrey) and Dr. Debbie Hopkins (University of Oxford), AVs may be spotted on our roads as soon 2025 and could lead to far-reaching impacts on urban tourism.The conceptual paper entitled “Autonomous vehicles and the future of urban tourism” imagines the impact of AVs in future urban tourism and focuses on the pros and cons of these impacts with regards to the transformation of urban space, the rise of autonomous taxis, and changes to city sightseeing and hospitality in the urban night.Potential benefits include reduced traffic congestion and emissions, improved foreign car hire processes, reduced parking requirements and cheaper taxi fares. AVs may impact other industries in radical ways too, such as Amsterdam’s Red Light District, which could become operated out of moving AVs, and restaurants and hotels may encounter new competition in the form of AV dining cars and passengers sleeping in their moving vehicles.AVs are also the subject of many concerns. More time spent in cars on longer journeys could facilitate greater urban sprawl and increase car dependency. AVs may reduce demand for train travel, coach tours, public transport and driven taxis—all resulting in future job losses. The potential for terrorism facilitated by AVs also raises genuine security fears.Professor Cohen, Head of Tourism and Transport at Surrey’s School of Hospitality and Tourism Management, said: “This groundbreaking study will benefit urban planners, policy makers and the tourism and hospitality industries, who will face a range of threats and opportunities as AVs begin to reach the mass market in the coming decade.”The visitor economy will be gradually transformed if AVs become fully automated and mainstream, leading to a future where hordes of small AVs could congest urban attractions, hop-on hop-off city bus tours may go out of business altogether, motorways between cities could fill at night with slow-moving AVs carrying sleeping occupants and commercial sex in moving AVs becomes a growing phenomenon.”The paper calls for future work that provides context-specific analyses that may reveal alternative ways of thinking about AVs for urban tourism. Its release coincides this week with the World Travel Market and European Tourism Day on 7 November and acts as a timely reminder of the rising importance and significance of AVs in tourism to industry and policy makers. Citation: Autonomous vehicles could shape the future of urban tourism (2018, November 7) retrieved 17 July 2019 from https://phys.org/news/2018-11-autonomous-vehicles-future-urban-tourism.html
© 2019 AFP Shares of electric carmaker Tesla Motors were under pressure Thursday following the surprise replacement of the company’s chief financial officer. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Shares of Tesla declined following the surprise replacement of its chief financial officer. Chief Executive Elon Musk announced the shift in the final moments of an earnings conference call on Wednesday night, saying Deepak Ahuja, 56, would be replaced by Zach Kirkhorn, currently a vice president in finance.Ahuja’s departure follows other executive turnover at the hard-charging Musk’s electric car company.Tesla shares were down 0.4 percent at $307.42 at mid-morning after falling as much as 4.8 percent earlier in the session.A note from JPMorgan Chase highlighted the exit as a key disappointment following Tesla’s mixed results, citing the outgoing executive’s “long automotive industry experience” and 11 years at the company.Ahuja “provided relative stability to the firm’s finance staff that has otherwise seen a great deal of churn,” the JPMorgan note said.A Canaccord Genuity note said Ahuja’s exit was “likely to stir investor concerns around corporate culture of Tesla, which has been a concern in the past.”Kirkhorn, 34, who started at Tesla in 2010 and returned after a stint at Harvard Business School, told analysts the company was in a “strong” financial position.”We have enough cash to continue launching new programs and developing new technologies and we’re able to service upcoming debt obligations with our forecasted cash flows,” he said.Tesla on Wednesday reported fourth-quarter profits of $139.6 million, up from a loss of $675.4 million in the year-ago period.Revenues more than doubled to $7.2 billion, reflecting the ramp-up of the company’s Model 3 sedan.Musk remained upbeat about the company’s prospects and sales, saying that while 2018 was a challenging year, it also was the most successful. Citation: Tesla shares fall after surprise CFO exit (2019, January 31) retrieved 17 July 2019 from https://phys.org/news/2019-01-tesla-fall-cfo-exit.html Tesla shares fall again on doubts about go-private deal
SHARE SHARE EMAIL COMMENT Published on May 03, 2019 The Karnataka government is planning to come out with a GI (geographical indication) Policy in the State, according to an official of the State government.In an informal chat with mediapersons on the sidelines of an interactive meeting with exporters at the Kanara Chamber of Commerce and Industry (KCCI) in Mangaluru on Friday, SR Satheesha, Managing Director of the Bengaluru-based Visvesvaraya Trade Promotion Centre (a Karnataka government organisation), said the State has 45 GI products in different sectors, including handicraft, horticulture, etc. Karnataka has maximum number of GI products among other states in the country.Stating that VTPC (Visvesvaraya Trade Promotion Centre ) is working on a strategy document on GI products in the State, he said: “We will have focussed meeting with the respective GI holders in the state. We will visit them to understand their issues, and to provide interventions wherever needed.”Highlighting the instances of gradual diminishing of some GI products in the State, he said the number of artisans producing ‘Udupi sari’ is coming down gradually. In such a situation, GI policy will help provide focused training programmes and skill upgradation facilities to the stakeholders of GI products.Apart from this, the policy will also want to make GI products competitive in the domestic and international markets. Considering this, plans are there to introduce concepts such as ‘GI tourism’, ‘GI exhibitions’, and ‘GI stores’ at airports, and also to develop ‘GI cluster’ in the State.Asked if any other State has taken initiative to launch a GI policy, he said Karnataka will be the first State to come out with a GI policy.Being niche in their segments, GI products have a lot of potential in the market. Somehow, they are not being marketed properly, Satheesha said. COMMENTS SHARE patent, copyright and trademark Karnataka
New cabinet ministers to be sworn in at 3 pm Saturday: Goa CM Pramod SawantGoa Chief Minister Pramod Sawant refused to name the MLAs who would be inducted but said all the four would be from the Bharatiya Janata Party, with three of them from the legislators who joined the party on Wednesday.advertisement Press Trust of India PanajiJuly 13, 2019UPDATED: July 13, 2019 04:58 IST Goa Chief Minister Pramod Sawant said the swearing-in ceremony would be held at 3 pm Saturday. (Photo: PTI)Goa Chief Minister Pramod Sawant said late on Friday night that he would reshuffle the cabinet on Saturday replacing four ministers and the swearing-in ceremony would be held at 3 pm.Ten Congress MLAs had on Wednesday joined the Bharatiya Janata Party (BJP) increasing the strength of the party to 27 on the floor of the House.Pramod Sawant said the three members from a coalition partner, Goa Forward Party, and an Independent MLA Rohan Khaunte would be dropped from the cabinet.Pramod Sawant refused to name the MLAs who would be inducted but said all the four would be from the BJP, with three of them from the legislators who joined the party on Wednesday.Speculations are rife that former leader of opposition Chandrakant Kavlekar, Philip Nery Rodrigues and Atanasio Monserratte would be inducted in the cabinet along with Deputy Speaker Michael Lobo.Pramod Sawant said the swearing-in ceremony would be held at 3 pm Saturday.This would the second cabinet reshuffle by Pramod Sawant since he took over as the chief minister three months ago. In his first cabinet reshuffle, Sawant had inducted MGP’s breakaway MLA Deepak Pauskar after dropping then deputy chief minister Sudin Dhavalikar.Asked why allies are being dropped from the cabinet, the chief minister said the decision has been taken as per directives of the central leadership.”I don’t want to go into details. We have taken this decision to give good governance to the people,” he said.Sawant has the support by three MLAs from the Goa Forward Party and an Independent.Goa Forward Party (GFP) chief and Deputy Chief Minister Vijai Sardesai had during the day said they are hoping for an amicable solution to the crisis.”The GFP is a part of the NDA and had joined the BJP-led government after talks with the saffron party’s national leadership,” Sardesai said, adding, “The present state BJP leaders were not part of the discussions then. As such, we will take appropriate steps only after talking to NDA leadership at the Centre.””We have not yet received any official communication from the BJP leaders. On the contrary, we have received indications that the matter will be sorted out amicably,” he said.Ten of the 15 Congress MLAs, led by the leader of Opposition, Chandrakant Kavlekar, switched sides and joined the Bharatiya Janata Party (BJP) on Wednesday.While the 10 MLAs and Lobo returned from Delhi, Sawant stayed back to attend a high-level meeting on Friday evening on the issue of mining in Goa, which has come to a standstill following a February 2018 Supreme Court order.Also Read | Goa CM Pramod Sawant seeks resignation of 3 ministers, independent MLA to induct new facesAlso Watch | Leaderless Congress headed towards self-destruction?For the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byAkriti Anand Next